Basil T Darras Selected Research

nusinersen

1/2022	Nusinersen for Patients With Spinal Muscular Atrophy: 1415 Doses via an Interdisciplinary Institutional Approach.
6/2021	Nusinersen Treatment in Adults With Spinal Muscular Atrophy.
1/2021	Age related treatment effect in type II Spinal Muscular Atrophy pediatric patients treated with nusinersen.
1/2021	Dysphagia Phenotypes in Spinal Muscular Atrophy: The Past, Present, and Promise for the Future.
1/2021	Nusinersen in pediatric and adult patients with type III spinal muscular atrophy.
10/2019	Nusinersen improves walking distance and reduces fatigue in later-onset spinal muscular atrophy.
1/2019	An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical Trials.
1/2019	Nusinersen in later-onset spinal muscular atrophy: Long-term results from the phase 1/2 studies.
1/2018	Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy.
11/2017	Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Basil T Darras Research Topics

Disease

24	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 12/2007
18	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 01/2022 - 02/2007
7	Disease Progression 10/2020 - 02/2015
4	Neuromuscular Diseases (Neuromuscular Disease) 11/2021 - 01/2013
3	Spinal Muscular Atrophies of Childhood (Werdnig Hoffman Disease) 01/2021 - 10/2012
3	Rhabdomyolysis 01/2020 - 03/2004
3	Paralysis (Palsy) 01/2020 - 07/2003
3	Polyneuropathies (Polyneuropathy) 01/2020 - 06/2008
3	Muscular Diseases (Myopathy) 09/2016 - 01/2007
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022 - 01/2019
2	Vomiting 01/2022 - 01/2019
2	Fever (Fevers) 01/2021 - 01/2019
2	Muscle Hypotonia (Hypotonia) 04/2020 - 10/2013
2	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 01/2020 - 07/2009
2	Myasthenia Gravis 01/2020 - 05/2014
2	Apnea 01/2020 - 07/2009
2	Crohn Disease (Crohn's Disease) 11/2016 - 02/2005
2	Muscle Weakness 07/2013 - 03/2004
2	Neoplasms (Cancer) 02/2011 - 04/2009
2	Muscular Dystrophies (Muscular Dystrophy) 10/2009 - 04/2008
1	Congenital Abnormalities (Deformity) 01/2022
1	Body Weight (Weight, Body) 11/2021
1	Deglutition Disorders (Dysphagia) 01/2021
1	Hydrocephalus (Hydrocephaly) 01/2021
1	Hereditary Spastic Paraplegia 10/2020
1	Polymicrogyria 10/2020
1	Intellectual Disability (Idiocy) 04/2020
1	Guillain-Barre Syndrome 01/2020
1	acute flaccid myelitis 01/2020
1	Botulism 01/2020
1	Respiratory Insufficiency (Respiratory Failure) 01/2020
1	Fatigue 10/2019
1	Headache (Headaches) 01/2019
1	Constipation 01/2019
1	Nasopharyngitis 01/2019
1	Rare Diseases (Rare Disease) 12/2017
1	Nondystrophic myotonia 01/2017
1	Channelopathies 01/2017
1	Myotonia Congenita (Thomsen Disease) 01/2017
1	Potassium aggravated myotonia 01/2017
1	Cardiomyopathies (Cardiomyopathy) 08/2015
1	Lambert-Eaton Myasthenic Syndrome (Lambert-Eaton Syndrome) 01/2014
1	Infantile onset spinocerebellar ataxia 10/2013
1	Facial Nerve Diseases (Facial Nerve Disorders) 10/2013
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 10/2013
1	Tremor (Tremors) 10/2013
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 07/2013
1	Myofibrillar Myopathy 07/2013
1	Congenital Structural Myopathies (Centronuclear Myopathy) 06/2012
1	Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) 12/2011
1	Nerve Sheath Neoplasms (Nerve Sheath Neoplasm) 02/2011
1	Liver Diseases (Liver Disease) 01/2011
1	Chronic Granulomatous Disease 06/2010

Drug/Important Bio-Agent (IBA)

11	nusinersenIBA 01/2022 - 03/2016
10	Biomarkers (Surrogate Marker)IBA 01/2020 - 07/2014
6	Proteins (Proteins, Gene)FDA Link 11/2021 - 10/2005
4	SteroidsIBA 05/2018 - 04/2009
3	deflazacortIBA 01/2022 - 01/2020
3	Prednisone (Sone)FDA LinkGeneric 01/2022 - 01/2020
3	Nonsense Codon (Nonsense Mutation)IBA 12/2021 - 11/2018
3	atalurenIBA 12/2021 - 11/2018
3	Pharmaceutical PreparationsIBA 01/2020 - 12/2013
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2017
2	Prednisolone (Predate)FDA LinkGeneric 12/2021 - 01/2020
2	RisdiplamIBA 11/2021 - 01/2021
2	reldesemtivIBA 07/2021 - 01/2021
2	ZolgensmaIBA 01/2021 - 01/2021
2	Transaminases (Aminotransferases)IBA 01/2021 - 01/2011
2	SpectrinIBA 04/2020 - 10/2013
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 11/2017
2	Thalidomide (Thalomid)FDA Link 11/2016 - 02/2005
2	EnzymesIBA 01/2011 - 05/2006
1	TroponinIBA 01/2021
1	IronIBA 10/2020
1	Adaptor Protein Complex 4IBA 10/2020
1	ElectrolytesIBA 01/2020
1	PotassiumIBA 01/2020
1	ChloridesIBA 01/2017
1	Ion Channels (Ion Channel)IBA 01/2017
1	SodiumIBA 01/2017
1	Antisense OligonucleotidesIBA 03/2016
1	Messenger RNA (mRNA)IBA 03/2016
1	Creatine Kinase (Creatine Phosphokinase)IBA 08/2015
1	Anesthetics (Anesthetic Agents)IBA 08/2015
1	Intravenous Immunoglobulins (IVIG)FDA Link 05/2014
1	NucleotidesIBA 10/2013
1	DesminIBA 07/2013
1	Blood Proteins (Serum Proteins)IBA 01/2013
1	Biological ProductsIBA 10/2012
1	GTP Phosphohydrolases (GTPases)IBA 06/2012
1	Dynamin IIIBA 06/2012
1	ElementsIBA 01/2011
1	DystrophinIBA 06/2010

Therapy/Procedure

13	Therapeutics 01/2021 - 07/2009
2	Spinal Fusion (Spondylosyndesis) 01/2022 - 02/2007
2	Aftercare (After-Treatment) 06/2021 - 02/2011
2	Immunomodulation 01/2014 - 12/2011
1	Investigational Therapies (Experimental Therapy) 01/2022
1	Plasmapheresis 05/2014
1	Stem Cell Transplantation 06/2010